Company History - Highlights
| 2011 |
Omicia collaborator Dr. Mark Yandell presented our Variant Annotation and Selection Tool (VAAST) – ‘A probabilistic disease–gene finder for personal genomes’ at the Cold Spring Harbor Laboratory Biology of Genomes conference. Read news coverage in Forbes. Co-authored analysis of the first 10 publicly available human genomes “Global analysis of disease-related DNA sequence variation in 10 healthy individuals: Implications for whole genome-based clinical diagnostics” published in Genetics in Medicine. Read news coverage in Bio-IT World. |
| 2010 |
Awarded SBIR Phase I grant from the National Library of Medicine for a collaboration with Dr. Karen Eilbeck, Assistant Professor, Department for Biomedical Information, University of Utah, School of Medicine, to create an ontology for DNA sequence variant annotations under the umbrella of the Sequence Ontology and GO ontology with the focus on Cardiovascular Disease as the model. Awarded a SBIR Phase I grant from the National Human Genome Research Institute for a collaboration with Dr. Joel Bader, Associate Professor, Department of Bioinformatics at Johns Hopkins University to develop and apply new statistical methods for identifying genetic hotspots for disease risk using DNA arrays or genome sequence. Omicia is one of the founding members of the Genomic Cancer Care Alliance, aimed at determining whether and how whole-genome sequencing can better guide treatment decisions across a number of difficult-to-treat cancers. Omicia will provide whole-genome interpretation service for the alliance. |
| 2009 |
Awarded subcontract to ARRA Stimulus GO Grant as part of collaboration with Dr. Mark Yandell’s group at the University of Utah to develop a whole-genome variant annotation, analysis and selection tool. Awarded SBIR Phase II grant for a collaboration with the University of Utah as a subcontractor to develop a gene inference system for disease genes. Contributed analysis for Genome Research paper describing the first human genome sequenced on LIFE’s SOLiD sequencing technology: "Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding." |
| 2008 |
Awarded SBIR Phase II grant to develop an IT system for genomic marker delivery based on genotyping arrays and whole genome
sequences for cardiovascular disease. Oral presentation "What can we learn from an individual genome—Personal genomes analyzed for disease-predisposing alleles" at the inaugural "Personal Genomes" meeting at Cold Spring Harbor Laboratory, 2008. Read Press Coverage: Nature, Oct 08 and Nature, Nov 08. |
| 2007 |
Awarded NIH STTR Phase I grant in collaboration with Johns Hopkins University for collaboration to identify genetic causes of cardiovascular disease. Read Press Release. Presented a poster about our OMIM mapping project at the 2007 Cold Spring Harbor Laboratory "Biology of Genomes" Conference: "Disease-Predisposition Alleles in the Human Genome." |
| 2006 |
Awarded SBIR Phase II NIH Grant to develop computational platform for mapping disease-relevant genetic mutations to the human genome assembly. Held Human Genome "Annotation Jamboree" at Omicia headquarters focusing on cardiovascular disease genes. Read article in BioInform (subscription required). PDF file |
| 2005 | Awarded SBIR Phase I grant to develop a prototype gene inference system in collaboration with the University of Utah. |
| 2004 | Awarded SBIR grant to develop prototype system for genetic marker information delivery. |
| 2003 | Awarded SBIR Phase I NIH grant to develop the prototype disease marker genome annotation system. |
| 2002 | Company founded. |