Enterprise - Fabric Genomics

Turn raw genomic data into clinical insights with Fabric Enterprise

Your comprehensive platform for NGS analysis, interpretation, and clinical reporting – powered by Fabric AI.

Fabric Enterprise is a turnkey, scalable platform

that speeds up clinical genomic analysis

Providing fast, accurate results for any clinical NGS test

Whole Genomes & Exomes

Rare and
Undiagnosed
Diseases

Ultra-rapid NICU
& PICU cases

Re-analysis of
negative cases

Hereditary & Oncology Panels

Cancer
Cardio
Neuro
Reproductive Health
Population Health

BRCA1 & BRCA
HBOC
Lynch syndrome
Colon
Inherited cancer syndromes

Familial hypercholesterolemia
Long QT
Marfan, aneurysm, & aortopathies
Cardiomyopathy
Arrhythmia

Non-syndromic epilepsies
Neuropathies

Newborn screening
Carrier screening

CDC Tier 1
ACMG secondary findings

Featuring a suite of algorithms that provide comprehensive analysis

Panel Testing
Hereditary risk screening
Pediatric testing

ACE
Automated variant
classification engine

VVP
Variant impact score

WGS / WES
Rapid NICU testing
Rare disease diagnoses

GEM
Next generation
disease gene ranking

VVP
Variant impact score

VAAST
Probabilistic gene burden ranking

Phevor
Phenotype-driven prioritization

Fabric is the solution of choice for leading genomics programs around the world

“GEM is the application of mathematics and AI to biology to get the most out of
a child’s genome to identify disease or find disease-causing gene mutations.”

Mark Yandell, Ph.D., Co-Direct USTAR Center for Genetic Discovery, Assoc.
Director Program in Personalized Health

Why Fabric Enterprise?

Near-instant identification of disease-causing genes in rare genetic disease diagnosis
Accurate alignment and variant calling
Up-to-date, validated variant annotation
Probabilistic variant ranking with advanced algorithms
Transparent logic and data sources
ACMG and AMP guideline-driven variant classification and interpretation
Configurable SOP-based workflows
Customizable clinical report generation
Full LIMS and EMR integration capabilities
CLIA compliant, HIPAA compliant, ISO-27001 certified

Ready to experience Fabric Enterprise?